CBD can interact with many other products. Certain drugs and supplements should never be combined, while other drugs and supplements may require adjustments in use. The effects of interactions will vary among different people, and are particularly common among older adults. Their bodies have changed and they often take many different medications.
Moreover, these changes make it more likely that CBD will interact with certain other substances. If you’re wondering what drugs should not be taken with CBD, keep reading to learn about some of these interactions.
People taking statins or other medications should consult a physician before beginning CBD treatment. Several medications interact with CYP enzymes, which break down drugs. Those who take these drugs should consult a doctor before beginning CBD therapy.
In addition, it’s important to remember that CBD can interfere with other medications that interact with the liver. People who are taking these drugs should avoid CBD before undergoing liver surgery or taking certain prescription medications.
Benzodiazepines and other anti-anxiety drugs should be avoided while taking CBD. These medications can increase CBD’s side effects and can interfere with your respiratory system. In addition, CBD can alter the effects of NSAIDs and antibiotics.
According to the District of Columbia Department of Health, CBD increases concentrations of these drugs in the blood. This can be a dangerous combination.
Because CBD inhibits the CYP450 system, it may inhibit the breakdown of certain medications. If your medications inhibit CYP3A4, CBD may interfere with the metabolism of those medications. When you’re on these drugs, CBD cannot process those medications, so you’ll end up with higher concentrations of these drugs. Additionally, it can increase your risk of bleeding or overdose. You can talk to your doctor or pharmacist to find out which drugs you can safely use with CBD.
Other drugs that interact with CBD include corticosteroids and other anti-inflammatory medications. Both CBD and corticosteroids can increase the risk of systemic side effects. Drugs that affect the metabolism of CBD are known as phase II metabolites. In addition to this, CBD may inhibit the activity of the CYP450 enzymes. These enzymes are important in the breakdown of many drugs, including CBD.
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NSAIDs can interact with CBD. These drugs lower bodily pain and inflammation. NSAIDs like ibuprofen may cause nausea, vomiting, or vertigo. They may also extend the duration of their negative effects. But there have been several studies in which the two drugs have synergistic effects when used together. If you’re concerned about the potential interactions between two drugs, talk to your doctor.
In addition to being incompatible with other medications, CBD can interfere with the function of liver enzymes. This can result in an altered concentration, making the medication less effective, and increasing the risk of side effects. Drug interactions are not always easy to predict, but they can have serious consequences. For instance, Epidiolex interacts with a number of prescription medications, including benzodiazepines and antipsychotics.
